Investigating the interaction between APOE genotype and Sex to Alzheimer?s Disease Lead Investigator: Yuan Shang Institution : University of Arizona E-Mail : yshang@email.arizona.edu Proposal ID : 1233 Proposal Description: Alzheimer's disease is well-known to be affected by risk factors such as age, sex and APOE genotypes. We developed models to evaluate the potential effect between different factors, and want to use the NACC datasets to do the validations. So at current stages, we only want the Age onset, age, sex, and APOE genotypes. Later, as research goes on, we may require other biomarker's information.